Pfizer-BioNTech vaccine
The Pfizer-BioNTech vaccine is a messenger RNA (mRNA) vaccine. It works by delivering a piece of mRNA that encodes the spike protein of the SARS-CoV-2 virus to the cells of the immune system. This causes the cells to produce spike proteins, which the immune system then recognizes as foreign and produces antibodies against.
The Pfizer-BioNTech vaccine was tested in a clinical trial involving more than 40,000 people. The results of the trial showed that the vaccine was 95% effective at preventing symptomatic COVID-19. The vaccine was also well-tolerated, with the most common side effects being pain at the injection site, fatigue, and headache.
Moderna vaccine
The Moderna vaccine is also an mRNA vaccine. It works in the same way as the Pfizer-BioNTech vaccine.
The Moderna vaccine was tested in a clinical trial involving more than 30,000 people. The results of the trial showed that the vaccine was 94% effective at preventing symptomatic COVID-19. The vaccine was also well-tolerated, with the most common side effects being pain at the injection site, fatigue, and headache.
Johnson & Johnson vaccine
The Johnson & Johnson vaccine is a viral vector vaccine. It works by delivering a weakened form of the adenovirus serotype 26 (Ad26) virus that has been modified to express the spike protein of the SARS-CoV-2 virus. This causes the cells to produce spike proteins, which the immune system then recognizes as foreign and produces antibodies against.
The Johnson & Johnson vaccine was tested in a clinical trial involving more than 40,000 people. The results of the trial showed that the vaccine was 66% effective at preventing moderate to severe COVID-19. The vaccine was also well-tolerated, with the most common side effects being pain at the injection site, fatigue, and headache.
Conclusion
The evidence from clinical trials shows that the new COVID-19 vaccines are safe and effective. The vaccines are highly effective at preventing symptomatic COVID-19 and are well-tolerated.
If you have any questions about the safety or efficacy of the COVID-19 vaccines, please talk to your doctor.
Kind regards E. Thompson